Found 186 results
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M. C. Hanson, Bershteyn, A., Crespo, M. P., and Irvine, D. J., Antigen Delivery by Lipid-Enveloped PLGA Microparticle Vaccines Mediated by in Situ Vesicle Shedding, Biomacromolecules, vol. 15, no. 7, pp. 2475 - 2481, 2014.
S. Pejawar-Gaddy, Kovacs, J. M., Barouch, D. H., Chen, B., and Irvine, D. J., Design of Lipid Nanocapsule Delivery Vehicles for Multivalent Display of Recombinant Env Trimers in HIV Vaccination, Bioconjugate Chemistry, vol. 25, no. 8, pp. 1470 - 1478, 2014.
Y. - S. Yang, Carney, R. P., Stellacci, F., and Irvine, D. J., Enhancing Radiotherapy by Lipid Nanocapsule-Mediated Delivery of Amphiphilic Gold Nanoparticles to Intracellular Membranes, Acs Nano, vol. 8, no. 9, pp. 8992 - 9002, 2014.
R. Brad Jones, O'Connor, R., Mueller, S., Foley, M., Szeto, G. L., Karel, D., Lichterfeld, M., Kovacs, C., Ostrowski, M. A., Trocha, A., Irvine, D. J., and Walker, B. D., Histone Deacetylase Inhibitors Impair the Elimination of HIV-Infected Cells by Cytotoxic T-Lymphocytes, Plos Pathogens, vol. 10, no. 8, 2014.
P. C. DeMuth, Min, Y., Irvine, D. J., and Hammond, P. T., Implantable Silk Composite Microneedles for Programmable Vaccine Release Kinetics and Enhanced Immunogenicity in Transcutaneous Immunization, Advanced Healthcare Materials, vol. 3, no. 1, pp. 47 - 58, 2014.
H. Liu, Moynihan, K. D., Zheng, Y., Szeto, G. L., Li, A. V., Huang, B., Van Egeren, D. S., Park, C., and Irvine, D. J., Structure-based programming of lymph-node targeting in molecular vaccines, Nature, vol. 507, no. 7493, p. 519 - +, 2014.
P. C. DeMuth, Garcia-Beltran, W. F., Ai-Ling, M. Lim, Hammond, P. T., and Irvine, D. J., Composite Dissolving Microneedles for Coordinated Control of Antigen and Adjuvant Delivery Kinetics in Transcutaneous Vaccination, Advanced Functional Materials, vol. 23, no. 2, pp. 161 - 172, 2013.
Y. Wang and Irvine, D. J., Convolution of chemoattractant secretion rate, source density, and receptor desensitization direct diverse migration patterns in leukocytes, Integrative Biology, vol. 5, no. 3, pp. 481 - 494, 2013.
R. C. Van Lehn, Atukorale, P. U., Carney, R. P., Yang, Y. - S., Stellacci, F., Irvine, D. J., and Alexander-Katz, A., Effect of Particle Diameter and Surface Composition on the Spontaneous Fusion of Monolayer-Protected Gold Nanoparticles with Lipid Bilayers, Nano Letters, vol. 13, no. 9, pp. 4060 - 4067, 2013.
J. Mata-Fink, Hanson, M. C., Falkowska, E., Burton, D., Irvine, D. J., and Wittrup, K., Engineered Immunogens that Raise Antibodies to a Single Epitope, Aids Research and Human Retroviruses, vol. 29, no. 11, pp. A25 - A25, 2013.
D. J. Irvine, Swartz, M. A., and Szeto, G. L., Engineering synthetic vaccines using cues from natural immunity, Nature Materials, vol. 12, no. 11, pp. 978 - 990, 2013.
M. E. Ackerman, Dugast, A. - S., McAndrew, E. G., Tsoukas, S., Licht, A. F., Irvine, D. J., and Alter, G., Enhanced Phagocytic Activity of HIV-Specific Antibodies Correlates with Natural Production of Immunoglobulins with Skewed Affinity for Fc gamma R2a and Fc gamma R2b, Journal of Virology, vol. 87, no. 10, pp. 5468 - 5476, 2013.
M. Kim, Song, L., Moon, J., Sun, Z. - Y. J., Bershteyn, A., Hanson, M., Cain, D., Goka, S., Kelsoe, G., Wagner, G., Irvine, D. J., and Reinherz, E. L., Immunogenicity of Membrane-bound HIV-1 gp41 Membrane-proximal External Region (MPER) Segments Is Dominated by Residue Accessibility and Modulated by Stereochemistry, Journal of Biological Chemistry, vol. 288, no. 44, pp. 31888 - 31901, 2013.
Y. Zheng, Stephan, M. T., S. Gai, A., Abraham, W., Shearer, A., and Irvine, D. J., In vivo targeting of adoptively transferred T-cells with antibody- and cytokine-conjugated liposomes, Journal of Controlled Release, vol. 172, no. 2, pp. 426 - 435, 2013.
A. Drake, Joshi, N. S., Szeto, G. L., Zhu, E. F., Eisen, H. N., and Irvine, D. J., Koch Institute Symposium on Cancer Immunology and Immunotherapy, Cancer Immunology Research, vol. 1, no. 4, pp. 217 - 222, 2013.
P. C. DeMuth, Moon, J. J., Suh, H., Hammond, P. T., and Irvine, D. J., Layer-by-layer assembly of lipid nanocapsules on microneedles for enhanced transcutaneous vaccine delivery, Abstracts of Papers of the American Chemical Society, vol. 245, 2013.
B. Kwong, S. Gai, A., Elkhader, J., K. Wittrup, D., and Irvine, D. J., Localized Immunotherapy via Liposome-Anchored Anti-CD137+IL-2 Prevents Lethal Toxicity and Elicits Local and Systemic Antitumor Immunity, Cancer Research, vol. 73, no. 5, pp. 1547 - 1558, 2013.
P. C. DeMuth, Min, Y., Huang, B., Kramer, J. A., Miller, A. D., Barouch, D. H., Hammond, P. T., and Irvine, D. J., Polymer multilayer tattooing for enhanced DNA vaccination, Nature Materials, vol. 12, no. 4, pp. 367 - 376, 2013.
J. Mata-Fink, Kriegsman, B., Yu, H. Xin, Zhu, H., Hanson, M. C., Irvine, D. J., and K. Wittrup, D., Rapid Conformational Epitope Mapping of Anti-gp120 Antibodies with a Designed Mutant Panel Displayed on Yeast, Journal of Molecular Biology, vol. 425, no. 2, pp. 444 - 456, 2013.
A. Li, Moon, J., and Irvine, D. J., Stabilized lipid nanocapsules eliciting potent mucosal immune response, Journal of Immunology, vol. 190, 2013.
H. Liu and Irvine, D. J., Structure-based programming of the immune response by molecular self-delivering vaccines, Abstracts of Papers of the American Chemical Society, vol. 246, 2013.
X. Su, Yang, N., K. Wittrup, D., and Irvine, D. J., Synergistic Antitumor Activity from Two-Stage Delivery of Targeted Toxins and Endosome-Disrupting Nanoparticles, Biomacromolecules, vol. 14, no. 4, pp. 1093 - 1102, 2013.
P. C. DeMuth, Li, A. V., Abbink, P., Liu, J., Li, H., Stanley, K. A., Smith, K. M., Lavine, C. L., Seaman, M. S., Kramer, J. A., Miller, A. D., Abraham, W., Suh, H., Elkhader, J., Hammond, P. T., Barouch, D. H., and Irvine, D. J., Vaccine delivery with microneedle skin patches in nonhuman primates, Nature Biotechnology, vol. 31, no. 12, pp. 1082 - 1085, 2013.