Publications

Found 152 results
Filters: Author is Darrell J. Irvine  [Clear All Filters]
2012
H. Liu and Irvine, D. J., Immunostimulatory properties of dynamic oligonucleotide micelles, Journal of Immunology, vol. 188, 2012.
B. Kwong, Liu, H., and Irvine, D. J., Intratumoral delivery of liposome-anchored anti-CD137 and IL-2 induces highly potent local and systemic anti-tumor immunity while minimizing toxic inflammatory side effects, Journal of Immunology, vol. 188, 2012.
J. Moon, Suh, H., Li, A., Yadava, A., and Irvine, D. J., Nanoparticle vaccines enhance humoral responses to a malaria antigen by expanding Tfh cells and inducing germinal center formation, Journal of Immunology, vol. 188, 2012.
C. M. Metallo, Gameiro, P. A., Bell, E. L., Mattaini, K. R., Yang, J., Hiller, K., Jewell, C. M., Johnson, Z. R., Irvine, D. J., Guarente, L., Kelleher, J. K., Heiden, M. G. Vander, Iliopoulos, O., and Stephanopoulos, G., Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia, Nature, vol. 481, no. 7381, pp. 380 - U166, 2012.
P. C. DeMuth, Moon, J. J., Suh, H., Hammond, P. T., and Irvine, D. J., Releasable Layer-by-Layer Assembly of Stabilized Lipid Nanocapsules on Microneedles for Enhanced Transcutaneous Vaccine Delivery, Acs Nano, vol. 6, no. 9, pp. 8041 - 8051, 2012.
M. E. Ackerman, Moldt, B., Wyatt, R. T., Dugast, A. - S., McAndrew, E., Tsoukas, S., Jost, S., Berger, C. T., Sciaranghella, G., Liu, Q., Irvine, D. J., Burton, D. R., and Alter, G., A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples (vol 376, pg 156, 2012), Journal of Immunological Methods, vol. 376, no. 1-2, pp. 156 - 156, 2012.
A. Bershteyn, Hanson, M. C., Crespo, M. P., Moon, J. J., Li, A. V., Suh, H., and Irvine, D. J., Robust IgG responses to nanograms of antigen using a biomimetic lipid-coated particle vaccine, Journal of Controlled Release, vol. 157, no. 3, pp. 354 - 365, 2012.
M. C. Hanson, Mata-Fink, J., Abraham, W., Wittrup, K. D., and Irvine, D. J., Shaping humoral responses against mini-libraries of HIV env antigens via lipid nanoparticle vaccine delivery, Retrovirology, vol. 9, 2012.
M. Stephan, Bak, S., Stephan, S., Chen, J., and Irvine, D. J., Synapse-directed delivery of immune-stimulants using T-cell-conjugated nanoparticles, Journal of Immunology, vol. 188, 2012.
M. T. Stephan, Stephan, S. B., Bak, P., Chen, J., and Irvine, D. J., Synapse-directed delivery of immunomodulators using T-cell-conjugated nanoparticles, Biomaterials, vol. 33, no. 23, pp. 5776 - 5787, 2012.
B. Huang and Irvine, D. J., Targeted chemotherapeutic delivery to disseminated lymphoma tumors via adoptive transfer of drug nanoparticle-carrying T cells, Journal of Immunology, vol. 188, 2012.
2011
J. - W. Yoo, Irvine, D. J., Discher, D. E., and Mitragotri, S., Bio-inspired, bioengineered and biomimetic drug delivery carriers, Nature Reviews Drug Discovery, vol. 10, no. 7, pp. 521 - 535, 2011.
V. Dahirel, Shekhar, K., Pereyra, F., Miura, T., Artyomov, M., Talsania, iv, S., Allen, T. M., Altfeld, M., Carrington, M., Irvine, D. J., Walker, B. D., and Chakraborty, A. K., Coordinate linkage of HIV evolution reveals regions of immunological vulnerability, Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 28, pp. 11530 - 11535, 2011.
D. J. Irvine, DRUG DELIVERY One nanoparticle, one kill, Nature Materials, vol. 10, no. 5, pp. 342 - 343, 2011.
Y. Wang and Irvine, D. J., Engineering chemoattractant gradients using chemokine-releasing polysaccharide microspheres, Biomaterials, vol. 32, no. 21, pp. 4903 - 4913, 2011.
M. T. Stephan and Irvine, D. J., Enhancing cell therapies from the outside in: Cell surface engineering using synthetic nanomaterials, Nano Today, vol. 6, no. 3, pp. 309 - 325, 2011.
A. T. Melvin, Welf, E. S., Wang, Y., Irvine, D. J., and Haugh, J. M., In Chemotaxing Fibroblasts, Both High-Fidelity and Weakly Biased Cell Movements Track the Localization of PI3K Signaling, Biophysical Journal, vol. 100, no. 8, pp. 1893 - 1901, 2011.
C. M. Jewell, Lopez, S. C. Bustama, and Irvine, D. J., In situ engineering of the lymph node microenvironment via intranodal injection of adjuvant-releasing polymer particles, Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 38, pp. 15745 - 15750, 2011.
X. Su, Fricke, J., Kavanagh, D. G., and Irvine, D. J., In Vitro and in Vivo mRNA Delivery Using Lipid-Enveloped pH-Responsive Polymer Nanoparticles, Molecular Pharmaceutics, vol. 8, no. 3, pp. 774 - 787, 2011.
B. Kwong, Liu, H., and Irvine, D. J., Induction of potent anti-tumor responses while eliminating systemic side effects via liposome-anchored combinatorial immunotherapy, Biomaterials, vol. 32, no. 22, pp. 5134 - 5147, 2011.
J. J. Moon, Suh, H., Bershteyn, A., Stephan, M. T., Liu, H., Huang, B., Sohail, M., Luo, S., Um, S. Ho, Khant, H., Goodwin, J. T., Ramos, J., Chiu, W., and Irvine, D. J., Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses, Nature Materials, vol. 10, no. 3, pp. 243 - 251, 2011.
H. Liu, Kwong, B., and Irvine, D. J., Membrane Anchored Immunostimulatory Oligonucleotides for In Vivo Cell Modification and Localized Immunotherapy, Angewandte Chemie-International Edition, vol. 50, no. 31, pp. 7052 - 7055, 2011.
C. M. Jewell, Jung, J. - M., Atukorale, P. U., Carney, R. P., Stellacci, F., and Irvine, D. J., Oligonucleotide Delivery by Cell-Penetrating "Striped" Nanoparticles, Angewandte Chemie-International Edition, vol. 50, no. 51, pp. 12312 - 12315, 2011.
M. - L. De Temmerman, Rejman, J., Demeester, J., Irvine, D. J., Gander, B., and De Smedt, S. C., Particulate vaccines: on the quest for optimal delivery and immune response, Drug Discovery Today, vol. 16, no. 13-14, pp. 569 - 582, 2011.
M. E. Ackerman, Moldt, B., Wyatt, R. T., Dugast, A. - S., McAndrew, E., Tsoukas, S., Jost, S., Berger, C. T., Sciaranghella, G., Liu, Q., Irvine, D. J., Burton, D. R., and Alter, G., A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples, Journal of Immunological Methods, vol. 366, no. 1-2, pp. 8 - 19, 2011.

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