Polina Anikeeva

  • Professor of Materials Science and Engineering
  • Professor in Brain and Cognitive Sciences
  • McGovern Institute for Brain Research
  • Associate Director, Research Laboratory of Electronics
  • B.S. in Biophysics, St. Petersburg State Polytechnic University, 2003
  • Ph.D. in Materials Science and Engineering, MIT, 2009


Bio; Biomaterials; Biophysics; Biotechnology; Electronic Materials; Magnetic Materials; Materials Chemistry; Implants; Nanotechnology; Photonic Materials

Polina Anikeeva


Prof. Polina Anikeeva joined DMSE in 2011. Dr. Anikeeva's Ph.D. thesis focussed on physical properties and design of light emitting devices based on organic materials and nanoparticles, working under the supervision of Prof. Vladimir Bulovic in EECS. She previously held the Dean's Postdoctoral Fellowship, School of Medicine, Stanford and was in the group of Prof. Karl Deisseroth in the Department of Bioengineering. Her current research is focused on development of optoelectronic and magnetic materials and devices for recording and modulating activity of neurons in the brain, spinal cord, and peripheral organs.

When asked to describe her research interests, Dr. Anikeeva writes, "My research interests lie within the field of Bioelectronics, and specifically the development of materials and devices that enable recording and manipulation of signaling processes within the nervous system. Our ability to understand the dynamics of neural circuits and develop treatments for neurological (Parkinson’s, paraplegia) and psychiatric (depression) conditions is currently handicapped by the technology available for interacting with the electrical, chemical, and mechanical signaling modalities used by neurons. Today, neural probes remain limited in both function and longevity as they fail to communicate with the neural tissue across its signaling palette for extended periods of time. ....By combining physical modeling, materials synthesis and device fabrication with understanding of electrophysiological and anatomical structure of neural circuits, my group aspires to create enabling tools for systems neuroscience as well as advance the development of future neuroprosthetics." She is enthusiastic about pursuing her research interests at MIT, where collaborations between colleagues, departments, and schools create innovations almost daily.

She explains that, "While research is a very significant part, of my life, I cannot possibly imagine a fulfilling career without teaching. My goal, as a teacher, is to infect the students with my curiosity for materials science and to inspire them to become future academic and industry leaders in the field." Every Spring she teaches core undergraduate course 3.024 "Electronic, Optical, and Magnetic Properties of Materials" that takes students on a math-packed journey throught the structure-property relations governing optoelectronics and magnetism. In the Fall she teaches an advanced design course 3.156/3.46 "Photonic Materials and Devices" that allows students to engineer realistic photonic devices such as lasers, solar cells, and optical fibers.

Recent News



K. Reidy et al., “Direct imaging and electronic structure modulation of moiré superlattices at the 2D/3D interface”, Nature Communications, vol. 12, no. 1. Springer Science and Business Media LLC, 2021.
M. A. Booth et al., “Fiber-Based Electrochemical Biosensors for Monitoring pH and Transient Neurometabolic Lactate”, Analytical Chemistry. American Chemical Society (ACS), 2021.
Y. Jin et al., “Skeletal Muscle Regeneration: Functional Skeletal Muscle Regeneration with Thermally Drawn Porous Fibers and Reprogrammed Muscle Progenitors for Volumetric Muscle Injury (Adv. Mater. 14/2021)”, Advanced Materials, vol. 33, no. 14. Wiley, p. 2170104, 2021.
J. Park, Koehler, F., Varnavides, G., Antonini, M. -J., and Anikeeva, P. O., “Influence of Magnetic Fields on Electrochemical Reactions of Redox Cofactor Solutions”, Angewandte Chemie. Wiley, 2021.
J. Park et al., “Electrochemical Modulation of Carbon Monoxide‐Mediated Cell Signaling”, Angewandte Chemie International Edition. Wiley, 2021.


Y. Guo et al., “Polymer-fiber-coupled field-effect sensors for label-free deep brain recordings”, PLOS ONE, vol. 15, no. 1. Public Library of Science (PLoS), p. e0228076, 2020.
J. Moon et al., “Magnetothermal Multiplexing for Selective Remote Control of Cell Signaling”, Advanced Functional Materials. Wiley, p. 2000577, 2020.
G. Varnavides, Jermyn, A. S., Anikeeva, P. O., Felser, C., and Narang, P., “Electron hydrodynamics in anisotropic materials”, Nature Communications, vol. 11, no. 1. Springer Science and Business Media LLC, 2020.
J. Park et al., “In situ electrochemical generation of nitric oxide for neuronal modulation”, Nature Nanotechnology, vol. 15, no. 8. Springer Science and Business Media LLC, pp. 690-697, 2020.
J. G. Sandland, Vargo, E., Paras, J., Varnavides, G., Warkander, S., and Anikeeva, P. O., “Electronic, Optical, and Magnetic Properties of Materials: A Comic-Based MOOC”, 2020 IEEE Learning With MOOCS (LWMOOCS). IEEE, 2020.
Y. Lee, Canales, A., Loke, G., Kanik, M., Fink, Y., and Anikeeva, P. O., “Selectively Micro-Patternable Fibers via In-Fiber Photolithography”, ACS Central Science. American Chemical Society (ACS), 2020.
J. A. Frank et al., “In Vivo Photopharmacology Enabled by Multifunctional Fibers”, ACS Chemical Neuroscience, vol. 11, no. 22. American Chemical Society (ACS), pp. 3802-3813, 2020.


M. Kanik et al., “Strain-programmable fiber-based artificial muscle”, Science, vol. 365. American Association for the Advancement of Science, pp. 145-150, 2019.
J. A. Frank, Antonini, M. -J., and Anikeeva, P. O., “Next-generation interfaces for studying neural function”, Nature Biotechnology. Springer Science and Business Media LLC, 2019.
S. Rao et al., “Remotely controlled chemomagnetic modulation of targeted neural circuits”, Nature Nanotechnology. Springer Science and Business Media LLC, 2019.
S. Park, Loke, G., Fink, Y., and Anikeeva, P. O., “Flexible fiber-based optoelectronics for neural interfaces”, Chemical Society Reviews, vol. 48, no. 6. Royal Society of Chemistry (RSC), pp. 1826-1852, 2019.
M. G. Christiansen, Senko, A. W., and Anikeeva, P. O., “Magnetic Strategies for Nervous System Control”, Annual Review of Neuroscience, vol. 42, no. 1. Annual Reviews, pp. 271-293, 2019.
D. Shahriari et al., “Scalable Fabrication of Porous Microchannel Nerve Guidance Scaffolds with Complex Geometries”, Advanced Materials, vol. 31, no. 30. Wiley, p. 1902021, 2019.
M. Roet, Hescham, S. -A., Jahanshahi, A., Rutten, B. P. F., Anikeeva, P. O., and Temel, Y., “Progress in neuromodulation of the brain: A role for magnetic nanoparticles?”, Progress in Neurobiology, vol. 177. Elsevier BV, pp. 1-14, 2019.


A. Kilias, Canales, A., Froriep, U. P., Park, S., Egert, U., and Anikeeva, P. O., “Optogenetic entrainment of neural oscillations with hybrid fiber probes”, Journal of Neural Engineering, vol. 15. p. 056006, 2018.
P. O. Anikeeva, Lieber, C. M., and Cheon, J., “Creating Functional Interfaces with Biological Circuits”, Accounts of Chemical Research, vol. 51. pp. 987-987, 2018.
B. Tian et al., “Roadmap on semiconductor–cell biointerfaces”, Physical Biology, vol. 15. p. 031002, 2018.
P. O. Anikeeva and Luo, L., “Editorial overview: Neurotechnologies”, Current Opinion in Neurobiology, vol. 50. p. iv—vi, 2018.
S. E. Mondello et al., “Optogenetic surface stimulation of the rat cervical spinal cord”, Journal of Neurophysiology, vol. 120. pp. 795-811, 2018.
A. Canales, Park, S., Kilias, A., and Anikeeva, P. O., “Multifunctional Fibers as Tools for Neuroscience and Neuroengineering”, Accounts of Chemical Research, vol. 51. pp. 829-838, 2018.


A. Canales, Park, S., Lu, C., Fink, Y., and Anikeeva, P. O., “Electronic, optical, and chemical interrogation of neural circuits with multifunctional fibers (Conference Presentation)”, in Biosensing and Nanomedicine X, San Diego, United States, 2017, p. 20.
C. Lu et al., “Flexible and stretchable nanowire-coated fibers for optoelectronic probing of spinal cord circuits”, Science Advances, vol. 3. p. e1600955, 2017.
M. G. Christiansen, Howe, C. M., Bono, D. C., Perreault, D. J., and Anikeeva, P. O., “Practical methods for generating alternating magnetic fields for biomedical research”, Review of Scientific Instruments, vol. 88. p. 084301, 2017.
S. Park et al., “One-step optogenetics with multifunctional flexible polymer fibers”, Nature Neuroscience, vol. 20. pp. 612-619, 2017.
S. Park et al., “One-step optogenetics with multifunctional flexible polymer fibers”, Nature Neuroscience, vol. 20. p. 612 - +, 2017.
R. Chen, Canales, A., and Anikeeva, P. O., “Neural recording and modulation technologies”, Nature Reviews Materials, vol. 2. p. 16093, 2017.


S. Schuerle, Dudani, J. S., Christiansen, M. G., Anikeeva, P. O., and Bhatia, S. N., “Magnetically Actuated Protease Sensors for in Vivo Tumor Profiling”, Nano Letters, vol. 16. pp. 6303-6310, 2016.
P. O. Anikeeva and Jasanoff, A., “Problems on the back of an envelope”, Elife, vol. 5. p. e19569, 2016.
G. Romero, Christiansen, M. G., Barbosa, L. S., Garcia, F., and Anikeeva, P. O., “Localized Excitation of Neural Activity via Rapid Magnetothermal Drug Release”, Advanced Functional Materials, vol. 26. pp. 6471-6478, 2016.
T. T. Ruckh et al., “Ion-Switchable Quantum Dot Forster Resonance Energy Transfer Rates in Ratiometric Potassium Sensors”, Acs Nano, vol. 10. pp. 4020-4030, 2016.
R. A. Koppes et al., “Thermally drawn fibers as nerve guidance scaffolds.”, Biomaterials, vol. 81. pp. 27-35, 2016.
R. Chen et al., “High-Performance Ferrite Nanoparticles through Nonaqueous Redox Phase Tuning”, Nano Letters, vol. 16. pp. 1345-1351, 2016.
P. O. Anikeeva, “Optogenetics unleashed.”, Nature biotechnology, vol. 34. pp. 43-4, 2016.


Y. Matsumoto, Chen, R., Anikeeva, P. O., and Jasanoff, A., “Engineering intracellular biomineralization and biosensing by a magnetic protein”, Nature Communications, vol. 6. p. 8721, 2015.
P. O. Anikeeva and Koppes, R. A., “Restoring the sense of touch”, Science, vol. 350. pp. 274-275, 2015.
C. N. Loynachan et al., “Targeted Magnetic Nanoparticles for Remote Magnetothermal Disruption of Amyloid-beta Aggregates”, Advanced Healthcare Materials, vol. 4. pp. 2100-2109, 2015.
S. Park et al., “Optogenetic control of nerve growth”, Scientific Reports, vol. 5. p. 9669, 2015.
R. Chen, Romero, G., Christiansen, M. G., Mohr, A., and Anikeeva, P. O., “Wireless magnetothermal deep brain stimulation”, Science, vol. 347. pp. 1477-1480, 2015.
A. Canales et al., “Multifunctional fibers for simultaneous optical, electrical and chemical interrogation of neural circuits in vivo.”, Nature biotechnology, vol. 33. pp. 277-84, 2015.


C. Lu et al., “Polymer Fiber Probes Enable Optical Control of Spinal Cord and Muscle Function In Vivo”, Advanced Functional Materials, vol. 24. pp. 6594-6600, 2014.
L. A. Gunaydin et al., “Natural Neural Projection Dynamics Underlying Social Behavior”, Cell, vol. 157. pp. 1535-1551, 2014.
K. Birmingham et al., “Bioelectronic medicines: a research roadmap”, Nature Reviews Drug Discovery, vol. 13. pp. 399-400, 2014.
R. Pashaie et al., “Optogenetic brain interfaces.”, IEEE reviews in biomedical engineering, vol. 7. pp. 3-30, 2014.


H. Liske, Qian, X., Anikeeva, P. O., Deisseroth, K., and Delp, S., “Optical control of neuronal excitation and inhibition using a single opsin protein, ChR2”, Scientific Reports, vol. 3. p. 3110, 2013.
R. Chen, Christiansen, M. G., and Anikeeva, P. O., “Maximizing Hysteretic Losses in Magnetic Ferrite Nanoparticles via Model-Driven Synthesis and Materials Optimization”, Acs Nano, vol. 7. pp. 8990-9000, 2013.
H. Liske et al., “Optical inhibition of motor nerve and muscle activity in vivo”, Muscle & Nerve, vol. 47. pp. 916-921, 2013.


P. O. Anikeeva and Deisseroth, K., “Photothermal Genetic Engineering”, Acs Nano, vol. 6. pp. 7548-7552, 2012.
P. O. Anikeeva et al., “Optetrode: a multichannel readout for optogenetic control in freely moving mice”, Nature Neuroscience, vol. 15. pp. 163 - U204, 2012.


K. E. Aidala, Panzer, M. J., Anikeeva, P. O., Halpert, J. E., Bawendi, M. G., and Bulovic, V., “Morphology of contact printed colloidal quantum dots in organic semiconductor films: Implications for QD-LEDs”, in Physica Status Solidi C: Current Topics in Solid State Physics, Vol 8, vol. 8, 2011.
K. E. Aidala, Panzer, M. J., Anikeeva, P. O., Halpert, J. E., Bawendi, M. G., and Bulovic, V., “Morphology of contact printed colloidal quantum dots in organic semiconductor films: Implications for QD-LEDs”, in Physica Status Solidi C: Current Topics in Solid State Physics, Vol 8, vol. 8, 2011.


I. B. Witten et al., “Cholinergic Interneurons Control Local Circuit Activity and Cocaine Conditioning”, Science, vol. 330. pp. 1677-1681, 2010.
M. J. Panzer, Aidala, K. E., Anikeeva, P. O., Halpert, J. E., Bawendi, M. G., and Bulovic, V., “Nanoscale Morphology Revealed at the Interface Between Colloidal Quantum Dots and Organic Semiconductor Films”, Nano Letters, vol. 10. pp. 2421-2426, 2010.
M. R. Hummon et al., “Measuring charge trap occupation and energy level in CdSe/ZnS quantum dots using a scanning tunneling microscope”, Physical Review B, vol. 81. 2010.
Y. Shirasaki, Anikeeva, P. O., Tischler, J. R., Bradley, S., and Bulovic, V., “Efficient Forster energy transfer from phosphorescent organic molecules to J-aggregate thin films”, Chemical Physics Letters, vol. 485. pp. 243-246, 2010.


P. O. Anikeeva, Halpert, J. E., Bawendi, M. G., and Bulovic, V., “Quantum Dot Light-Emitting Devices with Electroluminescence Tunable over the Entire Visible Spectrum”, Nano Letters, vol. 9. pp. 2532-2536, 2009.


L. A. Kim, Anikeeva, P. O., Coe-Sullivan, S. A., Steckel, J. S., Bawendi, M. G., and Bulovic, V., “Contact Printing of Quantum Dot Light-Emitting Devices”, Nano Letters, vol. 8. pp. 4513-4517, 2008.
P. O. Anikeeva, Madigan, C. F., Halpert, J. E., Bawendi, M. G., and Bulovic, V., “Electronic and excitonic processes in light-emitting devices based on organic materials and colloidal quantum dots”, Physical Review B, vol. 78. 2008.


P. O. Anikeeva, Halpert, J. E., Bawendi, M. G., and Bulovic, V., “Electroluminescence from a mixed red-green-blue colloidal quantum dot monolayer”, Nano Letters, vol. 7. pp. 2196-2200, 2007.


P. O. Anikeeva, Madigan, C. F., Coe-Sullivan, S. A., Steckel, J. S., Bawendi, M. G., and Bulovic, V., “Photoluminescence of CdSe/ZnS core/shell quantum dots enhanced by energy transfer from a phosphorescent donor”, Chemical Physics Letters, vol. 424. pp. 120-125, 2006.
J. S. Steckel et al., “Color-saturated green-emitting QD-LEDs”, Angewandte Chemie-International Edition, vol. 45. pp. 5796-5799, 2006.


S. A. Ivanov et al., “Light amplification using inverted core/shell nanocrystals: Towards lasing in the single-exciton regime”, Journal of Physical Chemistry B, vol. 108. pp. 10625-10630, 2004.