News: Ming Dao

Ming Dao Research on Sickle Cells

One of the most common complications of sickle-cell disease occurs when deformed red blood cells clump together, blocking tiny blood vessels and causing severe pain and swelling in the affected body parts. A new study from MIT sheds light on how these events, known as vaso-occlusive pain…  

How to bend and stretch a diamond

Diamond is well-known as the strongest of all natural materials, and with that strength comes another tightly linked property: brittleness. But now, an international team of researchers from MIT, Hong Kong, Singapore, and Korea has found that when grown in extremely tiny, needle-like shapes,…  

New property found in unusual crystalline materials

Most metals and semiconductors, from the steel in a knife blade to the silicon in a solar panel, are made up of many tiny crystalline grains. The way these grains meet at their edges can have a major impact on the solid’s properties, including mechanical strength, electrical conductivity,…  

Blood testing via sound waves may replace some tissue biopsies

Cells secrete nanoscale packets called exosomes that carry important messages from one part of the body to another. Scientists from MIT and other institutions have now devised a way to intercept these messages, which could be used to diagnose problems such as cancer or fetal abnormalities.…  

Discovery could help treatments for sickle cell disease

DMSE's Ming Dao, along with Postdoc Peter T.C. So, co-authored a study regarding sickle cell disease and the hydroxyurea action. "Our findings shine a light on the mechanism behind hydroxyurea action, which has long been debated in the scientific…  

How the spleen filters blood

Subra Suresh and Ming Dao have discovered that the shape and size of blood cells is determined by a tiny opening in the spleen called the interendothelial slit, where the cells undergo a sort of "physical fitness test" before they're able to continue circulating.  " '…  

Using sound waves to detect rare cancer cells

Cancer cells often break free from their original locations and circulate through the bloodstream, allowing them to form new tumors elsewhere in the body. Detecting these cells could give doctors a new way to predict whether patients’ tumors will metastasize, or monitor how they are responding…  

Probing the Malarial Shape Shifters

Last November, GlaxoSmithKline reported a disappointing 30 percent effectiveness in a trial for its RTS,S anti-malarial vaccine. RTS,S had been championed as the most promising vaccine for the mosquito-borne disease, which infects 300 to 500 million people a year while killing nearly one million…