Publications

Found 152 results
Filters: Author is Darrell J. Irvine  [Clear All Filters]
2015
B. Huang, Abraham, W. D., Zheng, Y., Lopez, S. C. Bustama, Luo, S. S., and Irvine, D. J., Active targeting of chemotherapy to disseminated tumors using nanoparticle-carrying T cells, Science Translational Medicine, vol. 7, no. 291, p. 291ra94, 2015.
E. L. Dane and Irvine, D. J., Big thinking for adjuvants, Nature Biotechnology, vol. 33, no. 11, pp. 1146 - 1148, 2015.
N. A. Hotaling, Tang, L., Irvine, D. J., and Babensee, J. E., Biomaterial Strategies for Immunomodulation, in Annual Review of Biomedical Engineering, Vol 17, vol. 17, M. L. Yarmush 2015, pp. 317 - 349.
K. B. Arnold, Szeto, G. L., Alter, G., Irvine, D. J., and Lauffenburger, D. A., CD4(+) T cell-dependent and CD4(+) T cell-independent cytokine-chemokine network changes in the immune responses of HIV-infected individuals, Science Signaling, vol. 8, no. 399, p. ra104, 2015.
H. Liu and Irvine, D. J., Guiding Principles in the Design of Molecular Bioconjugates for Vaccine Applications, Bioconjugate Chemistry, vol. 26, no. 5, pp. 791 - 801, 2015.
S. B. Kudchodkar, Tang, L., Jeng, E. K., Wong, H. C., Irvine, D. J., and Maus, M. V., Improving CAR T Cell Efficacy for Solid Tumors By Nanogel-Based Delivery of Immunomodulatory Proteins, Molecular Therapy, vol. 23, pp. S207 - S207, 2015.
P. U. Atukorale, Yang, Y. - S., Bekdemir, A., Carney, R. P., Silva, P. J., Watson, N., Stellacci, F., and Irvine, D. J., Influence of the glycocalyx and plasma membrane composition on amphiphilic gold nanoparticle association with erythrocytes, Nanoscale, vol. 7, no. 26, pp. 11420 - 11432, 2015.
P. U. Atukorale, Yang, Y. - S., Bekdemir, A., Carney, R. P., Silva, P. J., Watson, N., Stellacci, F., and Irvine, D. J., Influence of the glycocalyx and plasma membrane composition on amphiphilic gold nanoparticle association with erythrocytes, Nanoscale, vol. 7, no. 26, pp. 11420 - 11432, 2015.
M. C. Hanson, Abraham, W., Crespo, M. P., Chen, S. H., Liu, H., Szeto, G. Lee, Kim, M., Reinherz, E. L., and Irvine, D. J., Liposomal vaccines incorporating molecular adjuvants and intrastructural T-cell help promote the immunogenicity of HIV membrane-proximal external region peptides, Vaccine, vol. 33, no. 7, pp. 861 - 868, 2015.
S. Wang, Mata-Fink, J., Kriegsman, B., Hanson, M., Irvine, D. J., Eisen, H. N., Burton, D. R., K. Wittrup, D., Kardar, M., and Chakraborty, A. K., Manipulating the Selection Forces during Affinity Maturation to Generate Cross-Reactive HIV Antibodies, Cell, vol. 160, no. 4, pp. 785 - 797, 2015.
S. Wang, Mata-Fink, J., Kriegsman, B., Hanson, M., Irvine, D. J., Eisen, H. N., Burton, D. R., K. Wittrup, D., Kardar, M., and Chakraborty, A. K., Manipulating the Selection Forces during Affinity Maturation to Generate Cross-Reactive HIV Antibodies, Cell, vol. 160, no. 4, pp. 785 - 797, 2015.
G. Lee Szeto, Van Egeren, D., Worku, H., Sharei, A., Alejandro, B., Park, C., Frew, K., Brefo, M., Mao, S., Heimann, M., Langer, R., Jensen, K. F., and Irvine, D. J., Microfluidic squeezing for intracellular antigen loading in polyclonal B-cells as cellular vaccines, Scientific Reports, vol. 5, p. 10276, 2015.
M. C. Hanson, Crespo, M. R., Abraham, W., Moynihan, K. D., Szeto, G. L., Chen, S. H., Melo, M. B., Mueller, S., and Irvine, D. J., Nanoparticu late STING agonists are potent lymph node-targeted vaccine adjuvants, Journal of Clinical Investigation, vol. 125, no. 6, pp. 2532 - 2546, 2015.
M. Castellarnau, Szeto, G. L., Su, H. - W., Tokatlian, T., Love, J. C., Irvine, D. J., and Voldman, J., Stochastic Particle Barcoding for Single-Cell Tracking and Multiparametric Analysis, Small, vol. 11, no. 4, pp. 489 - 498, 2015.
M. Castellarnau, Szeto, G. L., Su, H. - W., Tokatlian, T., Love, J. C., Irvine, D. J., and Voldman, J., Stochastic Particle Barcoding for Single-Cell Tracking and Multiparametric Analysis, Small, vol. 11, no. 4, pp. 489 - 498, 2015.
E. F. Zhu, Gai, S. A., Opel, C. F., Kwan, B. H., Surana, R., Mihm, M. C., Kauke, M. J., Moynihan, K. D., Angelini, A., Williams, R. T., Stephan, M. T., Kim, J. S., Yaffe, M. B., Irvine, D. J., Weiner, L. M., Dranoff, G., and K. Wittrup, D., Synergistic Innate and Adaptive Immune Response to Combination Immunotherapy with Anti-Tumor Antigen Antibodies and Extended Serum Half-Life IL-2, Cancer Cell, vol. 27, no. 4, pp. 489 - 501, 2015.
2014
M. C. Hanson, Bershteyn, A., Crespo, M. P., and Irvine, D. J., Antigen Delivery by Lipid-Enveloped PLGA Microparticle Vaccines Mediated by in Situ Vesicle Shedding, Biomacromolecules, vol. 15, no. 7, pp. 2475 - 2481, 2014.
S. Pejawar-Gaddy, Kovacs, J. M., Barouch, D. H., Chen, B., and Irvine, D. J., Design of Lipid Nanocapsule Delivery Vehicles for Multivalent Display of Recombinant Env Trimers in HIV Vaccination, Bioconjugate Chemistry, vol. 25, no. 8, pp. 1470 - 1478, 2014.
Y. - S. Yang, Carney, R. P., Stellacci, F., and Irvine, D. J., Enhancing Radiotherapy by Lipid Nanocapsule-Mediated Delivery of Amphiphilic Gold Nanoparticles to Intracellular Membranes, Acs Nano, vol. 8, no. 9, pp. 8992 - 9002, 2014.
R. Brad Jones, O'Connor, R., Mueller, S., Foley, M., Szeto, G. L., Karel, D., Lichterfeld, M., Kovacs, C., Ostrowski, M. A., Trocha, A., Irvine, D. J., and Walker, B. D., Histone Deacetylase Inhibitors Impair the Elimination of HIV-Infected Cells by Cytotoxic T-Lymphocytes, Plos Pathogens, vol. 10, no. 8, 2014.
P. C. DeMuth, Min, Y., Irvine, D. J., and Hammond, P. T., Implantable Silk Composite Microneedles for Programmable Vaccine Release Kinetics and Enhanced Immunogenicity in Transcutaneous Immunization, Advanced Healthcare Materials, vol. 3, no. 1, pp. 47 - 58, 2014.
H. Liu, Moynihan, K. D., Zheng, Y., Szeto, G. L., Li, A. V., Huang, B., Van Egeren, D. S., Park, C., and Irvine, D. J., Structure-based programming of lymph-node targeting in molecular vaccines, Nature, vol. 507, no. 7493, p. 519 - +, 2014.

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