Publications

Found 186 results
Filters: Author is Darrell J. Irvine  [Clear All Filters]
2011
A. T. Melvin, Welf, E. S., Wang, Y., Irvine, D. J., and Haugh, J. M., In Chemotaxing Fibroblasts, Both High-Fidelity and Weakly Biased Cell Movements Track the Localization of PI3K Signaling, Biophysical Journal, vol. 100, no. 8, pp. 1893 - 1901, 2011.
C. M. Jewell, Lopez, S. C. Bustama, and Irvine, D. J., In situ engineering of the lymph node microenvironment via intranodal injection of adjuvant-releasing polymer particles, Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 38, pp. 15745 - 15750, 2011.
X. Su, Fricke, J., Kavanagh, D. G., and Irvine, D. J., In Vitro and in Vivo mRNA Delivery Using Lipid-Enveloped pH-Responsive Polymer Nanoparticles, Molecular Pharmaceutics, vol. 8, no. 3, pp. 774 - 787, 2011.
B. Kwong, Liu, H., and Irvine, D. J., Induction of potent anti-tumor responses while eliminating systemic side effects via liposome-anchored combinatorial immunotherapy, Biomaterials, vol. 32, no. 22, pp. 5134 - 5147, 2011.
J. J. Moon, Suh, H., Bershteyn, A., Stephan, M. T., Liu, H., Huang, B., Sohail, M., Luo, S., Um, S. Ho, Khant, H., Goodwin, J. T., Ramos, J., Chiu, W., and Irvine, D. J., Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses, Nature Materials, vol. 10, no. 3, pp. 243 - 251, 2011.
H. Liu, Kwong, B., and Irvine, D. J., Membrane Anchored Immunostimulatory Oligonucleotides for In Vivo Cell Modification and Localized Immunotherapy, Angewandte Chemie-International Edition, vol. 50, no. 31, pp. 7052 - 7055, 2011.
C. M. Jewell, Jung, J. - M., Atukorale, P. U., Carney, R. P., Stellacci, F., and Irvine, D. J., Oligonucleotide Delivery by Cell-Penetrating "Striped" Nanoparticles, Angewandte Chemie-International Edition, vol. 50, no. 51, pp. 12312 - 12315, 2011.
M. - L. De Temmerman, Rejman, J., Demeester, J., Irvine, D. J., Gander, B., and De Smedt, S. C., Particulate vaccines: on the quest for optimal delivery and immune response, Drug Discovery Today, vol. 16, no. 13-14, pp. 569 - 582, 2011.
M. E. Ackerman, Moldt, B., Wyatt, R. T., Dugast, A. - S., McAndrew, E., Tsoukas, S., Jost, S., Berger, C. T., Sciaranghella, G., Liu, Q., Irvine, D. J., Burton, D. R., and Alter, G., A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples, Journal of Immunological Methods, vol. 366, no. 1-2, pp. 8 - 19, 2011.
M. J. Palmer, Mahajan, V. S., Chen, J., Irvine, D. J., and Lauffenburger, D. A., Signaling thresholds govern heterogeneity in IL-7-receptor-mediated responses of naive CD8(+) T cells, Immunology and Cell Biology, vol. 89, no. 5, pp. 581 - 594, 2011.
N. Martinez-Martin, Fernandez-Arenas, E., Cemerski, S., Delgado, P., Turner, M., Heuser, J., Irvine, D. J., Huang, B., Bustelo, X. R., Shaw, A., and Alarcon, B., T Cell Receptor Internalization from the Immunological Synapse Is Mediated by TC21 and RhoG GTPase-Dependent Phagocytosis, Immunity, vol. 35, no. 2, pp. 208 - 222, 2011.
2010
R. P. Carney, Jung, J. - M., Irvine, D. J., and Stellacci, F., All hydrophilic surface moieties for cell-penetrating nanoparticles, Abstracts of Papers of the American Chemical Society, vol. 239, 2010.
D. J. Irvine, Combining cell therapy and nanoparticle drug delivery: Chemical cell surface engineering on live cells using nanoparticles, Abstracts of Papers of the American Chemical Society, vol. 240, 2010.
X. Su, Kavanagh, D., and Irvine, D. J., Cytosolic delivery mediated via electrostatic surface binding of mRNA to degradable lipid-coated polymeric nanoparticles, Abstracts of Papers of the American Chemical Society, vol. 240, 2010.
A. J. Swiston, Gilbert, J. B., Irvine, D. J., Cohen, R. E., and Rubner, M. F., Freely Suspended Cellular "Backpacks" Lead to Cell Aggregate Self-Assembly, Biomacromolecules, vol. 11, no. 7, pp. 1826 - 1832, 2010.
A. Swiston, Gilbert, J., Irvine, D. J., Cohen, R., and Rubner, M. F., Injectable cellular "Backpacks" lead to cell aggregate self-assembly, Abstracts of Papers of the American Chemical Society, vol. 240, 2010.
P. C. DeMuth, Su, X., Samuel, R. E., Hammond, P. T., and Irvine, D. J., Nano-Layered Microneedles for Transcutaneous Delivery of Polymer Nanoparticles and Plasmid DNA, Advanced Materials, vol. 22, no. 43, p. 4851 - +, 2010.
H. Phee, Dzhagalov, I., Mollenauer, M., Wang, Y., Irvine, D. J., Robey, E., and Weiss, A., Regulation of thymocyte positive selection and motility by GIT2, Nature Immunology, vol. 11, no. 6, pp. 503 - U70, 2010.
B. Huang and Irvine, D. J., Surface functionalization of lymphocytes as chemotherapeutic controlled release carriers, Abstracts of Papers of the American Chemical Society, vol. 240, 2010.
B. Kwong and Irvine, D. J., Synthesis and characterization of antibody-nanoparticle conjugates for locally sequestered tumor immunotherapy, Abstracts of Papers of the American Chemical Society, vol. 240, 2010.
J. J. Moon, Suh, H., Sohail, M., Bershteyn, A., Um, S. Ho, Stephan, M. T., Huang, B., and Irvine, D. J., Synthesis and characterization of interbilayer-crosslinked multilamellar vesicles for vaccine delivery, Abstracts of Papers of the American Chemical Society, vol. 240, 2010.
A. Bershteyn and Irvine, D. J., Synthesis and characterization of lipid-coated micro- and nano-particles co-displaying antigen and adjuvant as dose-sparing vaccine delivery vehicles, Abstracts of Papers of the American Chemical Society, vol. 240, 2010.
M. T. Stephan, Moon, J. J., Um, S. Ho, Bershteyn, A., and Irvine, D. J., Therapeutic Cell Engineering Using Surface-Conjugated Synthetic Nanoparticles, Journal of Immunotherapy, vol. 33, no. 8, pp. 866 - 866, 2010.
M. T. Stephan, Moon, J. J., Um, S. Ho, Bershteyn, A., and Irvine, D. J., Therapeutic cell engineering with surface-conjugated synthetic nanoparticles, Nature Medicine, vol. 16, no. 9, pp. 1035 - U135, 2010.
P. C. DeMuth, Hammond, P. T., and Irvine, D. J., Transcutaneous delivery of plasmid DNA and degradable polymer nanoparticles from multilayer-coated microneedle arrays, Abstracts of Papers of the American Chemical Society, vol. 240, 2010.

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