Publications

Found 152 results
Filters: Author is Darrell J. Irvine  [Clear All Filters]
2013
J. Mata-Fink, Hanson, M. C., Falkowska, E., Burton, D., Irvine, D. J., and Wittrup, K., Engineered Immunogens that Raise Antibodies to a Single Epitope, Aids Research and Human Retroviruses, vol. 29, no. 11, pp. A25 - A25, 2013.
D. J. Irvine, Swartz, M. A., and Szeto, G. L., Engineering synthetic vaccines using cues from natural immunity, Nature Materials, vol. 12, no. 11, pp. 978 - 990, 2013.
M. E. Ackerman, Dugast, A. - S., McAndrew, E. G., Tsoukas, S., Licht, A. F., Irvine, D. J., and Alter, G., Enhanced Phagocytic Activity of HIV-Specific Antibodies Correlates with Natural Production of Immunoglobulins with Skewed Affinity for Fc gamma R2a and Fc gamma R2b, Journal of Virology, vol. 87, no. 10, pp. 5468 - 5476, 2013.
M. Kim, Song, L., Moon, J., Sun, Z. - Y. J., Bershteyn, A., Hanson, M., Cain, D., Goka, S., Kelsoe, G., Wagner, G., Irvine, D. J., and Reinherz, E. L., Immunogenicity of Membrane-bound HIV-1 gp41 Membrane-proximal External Region (MPER) Segments Is Dominated by Residue Accessibility and Modulated by Stereochemistry, Journal of Biological Chemistry, vol. 288, no. 44, pp. 31888 - 31901, 2013.
Y. Zheng, Stephan, M. T., S. Gai, A., Abraham, W., Shearer, A., and Irvine, D. J., In vivo targeting of adoptively transferred T-cells with antibody- and cytokine-conjugated liposomes, Journal of Controlled Release, vol. 172, no. 2, pp. 426 - 435, 2013.
A. Drake, Joshi, N. S., Szeto, G. L., Zhu, E. F., Eisen, H. N., and Irvine, D. J., Koch Institute Symposium on Cancer Immunology and Immunotherapy, Cancer Immunology Research, vol. 1, no. 4, pp. 217 - 222, 2013.
P. C. DeMuth, Moon, J. J., Suh, H., Hammond, P. T., and Irvine, D. J., Layer-by-layer assembly of lipid nanocapsules on microneedles for enhanced transcutaneous vaccine delivery, Abstracts of Papers of the American Chemical Society, vol. 245, 2013.
B. Kwong, S. Gai, A., Elkhader, J., K. Wittrup, D., and Irvine, D. J., Localized Immunotherapy via Liposome-Anchored Anti-CD137+IL-2 Prevents Lethal Toxicity and Elicits Local and Systemic Antitumor Immunity, Cancer Research, vol. 73, no. 5, pp. 1547 - 1558, 2013.
P. C. DeMuth, Min, Y., Huang, B., Kramer, J. A., Miller, A. D., Barouch, D. H., Hammond, P. T., and Irvine, D. J., Polymer multilayer tattooing for enhanced DNA vaccination, Nature Materials, vol. 12, no. 4, pp. 367 - 376, 2013.
J. Mata-Fink, Kriegsman, B., Yu, H. Xin, Zhu, H., Hanson, M. C., Irvine, D. J., and K. Wittrup, D., Rapid Conformational Epitope Mapping of Anti-gp120 Antibodies with a Designed Mutant Panel Displayed on Yeast, Journal of Molecular Biology, vol. 425, no. 2, pp. 444 - 456, 2013.
A. Li, Moon, J., and Irvine, D. J., Stabilized lipid nanocapsules eliciting potent mucosal immune response, Journal of Immunology, vol. 190, 2013.
H. Liu and Irvine, D. J., Structure-based programming of the immune response by molecular self-delivering vaccines, Abstracts of Papers of the American Chemical Society, vol. 246, 2013.
X. Su, Yang, N., K. Wittrup, D., and Irvine, D. J., Synergistic Antitumor Activity from Two-Stage Delivery of Targeted Toxins and Endosome-Disrupting Nanoparticles, Biomacromolecules, vol. 14, no. 4, pp. 1093 - 1102, 2013.
P. C. DeMuth, Li, A. V., Abbink, P., Liu, J., Li, H., Stanley, K. A., Smith, K. M., Lavine, C. L., Seaman, M. S., Kramer, J. A., Miller, A. D., Abraham, W., Suh, H., Elkhader, J., Hammond, P. T., Barouch, D. H., and Irvine, D. J., Vaccine delivery with microneedle skin patches in nonhuman primates, Nature Biotechnology, vol. 31, no. 12, pp. 1082 - 1085, 2013.
2012
J. J. Moon, Suh, H., Polhemus, M. E., Ockenhouse, C. F., Yadava, A., and Irvine, D. J., Antigen-Displaying Lipid-Enveloped PLGA Nanoparticles as Delivery Agents for a Plasmodium vivax Malaria Vaccine, Plos One, vol. 7, no. 2, 2012.
Y. J. Yamanaka, Szeto, G. L., Gierahn, T. M., Forcier, T. L., Benedict, K. F., Brefo, M. S. N., Lauffenburger, D. A., Irvine, D. J., and J. Love, C., Cellular Barcodes for Efficiently Profiling Single-Cell Secretory Responses by Microengraving, Analytical Chemistry, vol. 84, no. 24, pp. 10531 - 10536, 2012.
D. J. Irvine and Liu, H., Dynamically stabilized oligonucleotide and peptide micelles for lymphoid tissue targeting: Designing vaccines one molecule at a time, Abstracts of Papers of the American Chemical Society, vol. 244, 2012.
A. Li, Moon, J., Elkhader, J., Yen, M., Abraham, W., Suh, H., and Irvine, D. J., Eliciting mucosal and systemic CD8+T-cell responses via pulmonary vaccination with synthetic nanoparticles, Journal of Immunology, vol. 188, 2012.
J. Mata-Fink, Hanson, M., Kriegsman, B., Irvine, D. J., and Wittrup, K., Engineered gp120 immunogens that elicit VRC01-like antibodies by vaccination, Retrovirology, vol. 9, 2012.
P. DeMuth, Huang, B., Min, Y., Barouch, D., Hammond, P., and Irvine, D. J., Engineered microneedle arrays for transcutaneous HIV vaccine delivery, Retrovirology, vol. 9, 2012.
P. DeMuth, Huang, B., Min, Y., Hammond, P., and Irvine, D. J., Engineered microneedle arrays for transcutaneous HIV vaccine delivery, Journal of Immunology, vol. 188, 2012.
J. J. Moon, Huang, B., and Irvine, D. J., Engineering Nano- and Microparticles to Tune Immunity, Advanced Materials, vol. 24, no. 28, pp. 3724 - 3746, 2012.
D. J. Irvine, Engineering nanoparticle interactions with cells via synergies in biochemistry and physical chemistry[p], Abstracts of Papers of the American Chemical Society, vol. 243, 2012.
C. Jewell, Lopez, S. Bustamante, and Irvine, D. J., Engineering the Lymph Node Microenvironment via Intranodal Controlled Release Vaccine Depots, Journal of Immunology, vol. 188, 2012.
J. J. Moon, Suh, H., Li, A. V., Ockenhouse, C. F., Yadava, A., and Irvine, D. J., Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand T-fh cells and promote germinal center induction, Proceedings of the National Academy of Sciences of the United States of America, vol. 109, no. 4, pp. 1080 - 1085, 2012.

Pages