Publications

Found 186 results
Filters: Author is Darrell J. Irvine  [Clear All Filters]
2017
B. R. Jones, Mueller, S., Kumari, S., Vrbanac, V., Genel, S., Tager, A. M., Allen, T. M., Walker, B. D., and Irvine, D. J., Antigen recognition-triggered drug delivery mediated by nanocapsule-functionalized cytotoxic T-cells, Biomaterials, vol. 117, pp. 44 - 53, 2017.
K. Rakhra, Zhu, E. F., Abraham, W., Moynihan, K. D., Mehta, N., Wittrup, K. D., and Irvine, D. J., Combination immunotherapy of an autochthonous murine lung cancer model expressing human CEA as a tumor-associated self-antigen, Cancer Immunology Research, vol. 5, no. 3, 2017.
L. Milling, Zhang, Y., and Irvine, D. J., Delivering safer immunotherapies for cancer, Advanced Drug Delivery Reviews, vol. 114, pp. 79 - 101, 2017.
W. L. Fotoran, Santangelo, R., de Mirand, B. N. M., Irvine, D. J., and Wunderlich, G., DNA-Loaded Cationic Liposomes Efficiently Function as a Vaccine against Malarial Proteins, Molecular Therapy-Methods & Clinical Development, vol. 7, pp. 1 - 10, 2017.
E. Janssen, Kumari, S., Tohme, M., Ullas, S., Barrera, V., Tas, J. M. J., Castillo-Rama, M., Bronson, R. T., Usmani, S. M., Irvine, D. J., Mempel, T. R., and Geha, R. S., DOCK8 enforces immunological tolerance by promoting IL-2 signaling and immune synapse formation in Tregs, Jci Insight, vol. 2, no. 19, p. e94298, 2017.
M. Pauthner, Havenar-Daughton, C., Sok, D., Nkolola, J. P., Bastidas, R., Boopathy, A. V., Carnathan, D. G., Chandrashekar, A., Cirelli, K. M., Cottrell, C. A., Eroshkin, A. M., Guenaga, J., Kaushik, K., Kulp, D. W., Liu, J., McCoy, L. E., Oom, A. L., Ozorowski, G., Post, K. W., Sharma, S. K., Steichen, J. M., de Taeye, S. W., Tokatlian, T., de la Pena, A. Torrents, Butera, S. T., LaBranche, C. C., Montefiori, D. C., Silvestri, G., Wilson, I. A., Irvine, D. J., Sanders, R. W., Schief, W. R., Ward, A. B., Wyatt, R. T., Barouch, D. H., Crotty, S., and Burton, D. R., Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches, Immunity, vol. 46, no. 6, p. 1073 - +, 2017.
Y. Zheng, Tang, L., Mabardi, L., Kumari, S., and Irvine, D. J., Enhancing Adoptive Cell Therapy of Cancer through Targeted Delivery of Small-Molecule Immunomodulators to Internalizing or Noninternalizing Receptors, Acs Nano, vol. 11, no. 3, pp. 3089 - 3100, 2017.
K. Dare Moynihan, Opel, C., Szeto, G., Tzeng, A., Eric, Z., Engreitz, J., Robert, W., Rakhra, K., Zhang, M., Rothschilds, A., Kumari, S., Kelly, R. L., Kwan, B., Abraham, W., Hu, K., Mehta, N., Kauke, M., Suh, H., Lauffenburger, D. A., K. Wittrup, D., and Irvine, D. J., Eradication of large established tumors with combination immunotherapy engaging innate and adaptive immunity, Cancer Immunology Research, vol. 5, no. 3, 2017.
S. Kumari, Moynihan, K., and Irvine, D. J., High-resolution visualization of immune response across the intact melanoma tumor, Cancer Immunology Research, vol. 5, no. 3, 2017.
Y. - S. Sabrina Yang, Atukorale, P. U., Moynihan, K. D., Bekdemir, A., Rakhra, K., Tang, L., Stellacci, F., and Irvine, D. J., High-throughput quantitation of inorganic nanoparticle biodistribution at the single-cell level using mass cytometry, Nature Communications, vol. 8, p. 14069, 2017.
Y. Fan, Kuai, R., Xup, Y., Ochyl, L. J., Irvine, D. J., and Moon, J. J., Immunogenic Cell Death Amplified by Co-localized Adjuvant Delivery for Cancer Immunotherapy, Nano Letters, vol. 17, no. 12, pp. 7387 - 7393, 2017.
Y. Zhang and Irvine, D. J., Nanoparticle-mediated systemic delivery of immune agonists to tumors enabling anti-tumor efficacy without toxicity, Cancer Immunology Research, vol. 5, no. 3, 2017.
O. K. Appelbe, Moynihan, K. D., Flor, A., Rymut, N., Irvine, D. J., and Kron, S. J., Radiation-enhanced delivery of systemically administered amphiphilic-CpG oligodeoxynucleotide, Journal of Controlled Release, vol. 266, pp. 248 - 255, 2017.
K. D. Moynihan and Irvine, D. J., Roles for Innate Immunity in Combination Immunotherapies, Cancer Research, vol. 77, no. 19, pp. 5215 - 5221, 2017.
W. Ngwa, Boateng, F., Kumar, iv, R., Irvine, D. J., Formenti, S., Ngoma, T., Herskind, C., Veldwijk, M. R., Hildenbrand, G. Lars, Hausmann, M., Wenz, F., and Hesser, J., Smart Radiation Therapy Biomaterials, International Journal of Radiation Oncology Biology Physics, vol. 97, no. 3, pp. 624 - 637, 2017.
J. Li, Wang, W., He, Y., Li, Y., Yan, E. Z., Zhang, K., Irvine, D. J., and Hammond, P. T., Structurally Programmed Assembly of Translation Initiation Nanoplex for Superior mRNA Delivery, Acs Nano, vol. 11, no. 3, pp. 2531 - 2544, 2017.
M. C. Hanson and Irvine, D. J., Synthesis of Lymph Node-Targeting Adjuvants, in Vaccine Adjuvants: Methods and Protocols, vol. 1494, C. B. Fox Totowa: Humana Press Inc, 2017, pp. 145 - 152.
Y. He, Li, J., Turvey, M. E., Funkenbusch, M. L. T., Hong, C., Uppu, D. S. S. M., He, H., Irvine, D. J., and Hammond, P. T., Synthetic Lift-off Polymer beneath Layer-by-Layer Films for Surface-Mediated Drug Delivery, Acs Macro Letters, vol. 6, no. 11, pp. 1320 - 1324, 2017.
D. Schmid, Park, C. Gwon, Hartl, C. A., Subedi, N., Cartwright, A. N., Puerto, R. Bou, Zheng, Y., Maiarana, J., Freeman, G. J., Wucherpfennig, K. W., Irvine, D. J., and Goldberg, M. S., T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity, Nature Communications, vol. 8, p. 1747, 2017.
2016
T. J. Moyer, Zmolek, A. C., and Irvine, D. J., Beyond antigens and adjuvants: formulating future vaccines, Journal of Clinical Investigation, vol. 126, no. 3, pp. 799 - 808, 2016.
L. Tang, Zheng, Y., Mabardi, L., and Irvine, D. J., Carrier-free delivery of cytokine to specifically expand adoptively transferred T cells for enhanced cancer immunotherapy, Cancer Immunology Research, vol. 4, no. 1, 2016.
E. F. Zhu, Rakhra, K., Mehta, N., Moynihan, K. D., Opel, C. F., Irvine, D. J., and K. Wittrup, D., Characterization and combination immunotherapy treatment of an inducible autochthonous murine lung cancer model expressing human carcinoembryonic antigen (CEA) as a tumor-associated self-antigen, Cancer Immunology Research, vol. 4, no. 1, 2016.
E. Janssen, Tohme, M., Hedayat, M., Leick, M., Kumari, S., Ramesh, N., Massaad, M. J., Ullas, S., Azcutia, V., Goodnow, C. C., Randall, K. L., Qiao, Q., Wu, H., Al-Herz, W., Cox, D., Hartwig, J., Irvine, D. J., Luscinskas, F. W., and Geha, R. S., A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton, Journal of Clinical Investigation, vol. 126, no. 10, pp. 3837 - 3851, 2016.
K. D. Moynihan, Opel, C. F., Szeto, G. L., Tzeng, A., Zhu, E. F., Engreitz, J. M., Williams, R. T., Rakhra, K., Zhang, M. H., Rothschilds, A. M., Kumari, S., Kelly, R. L., Kwan, B. H., Abraham, W., Hu, K., Mehta, N. K., Kauke, M. J., Suh, H., Cochran, J. R., Lauffenburger, D. A., K. Wittrup, D., and Irvine, D. J., Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses, Nature Medicine, vol. 22, no. 12, p. 1402 - +, 2016.

Pages