|Title||Assembly and organization processes in DNA-directed colloidal crystallization|
|Publication Type||Journal Article|
|Year of Publication||2009|
|Authors||Macfarlane, RJ, Lee, B, Hill, HD, Senesi, AJ, Seifert, S, Mirkin, CA|
|Journal||Proceedings of the National Academy of Sciences of the United States of America|
|Pagination||10493 - 10498|
We present an analysis of the key steps involved in the DNA-directed assembly of nanoparticles into crystallites and polycrystalline aggregates. Additionally, the rate of crystal growth as a function of increased DNA linker length, solution temperature, and self-complementary versus non-self-complementary DNA linker strands (1- versus 2-component systems) has been studied. The data show that the crystals grow via a 3-step process: an initial "random binding'' phase resulting in disordered DNA-AuNP aggregates, followed by localized reorganization and subsequent growth of crystalline domain size, where the resulting crystals are well-ordered at all subsequent stages of growth.